- Problem-Oriented Research Laboratory of Aerohydrodynamics and Acoustics
- Problem-Oriented Research Laboratory “Strength”
- Problem-Oriented Research Laboratory of Aviation Structures Durability
- Problem-Oriented Research Laboratory of Aircraft Manufacturing Technologies
- Problem-Oriented Research Laboratory of Gas Turbine Engines and Installations
- Problem-Oriented Research Laboratory of Aviation Engine Diagnostics
- Problem-Oriented Research Laboratory of Aircraft Control Systems
- Problem-Oriented Research Laboratory of Composite Materials
- Problem-Oriented Research Laboratory of Information Technologies and Systems
- Problem-Oriented Research Laboratory of Computer Technologies in Biomedical Engineering and Radioelectronics
- Problem-Oriented Research Laboratory of Radio Engineering and Navigation Systems
- Problem-Oriented Research Laboratory of Economic Mechanisms and Management in the Aviation Industry
- Problem-Oriented Research Laboratory for Human and Education Issues in Modern Sociocultural Dynamics